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Rifampicin reduced the bioluminescence of intracellular bacteria, consistent with its ability to penetrate mammalian cell membranes and inhibit bacterial transcription, thereby reducing metabolic activity (Fig

The mechanism involves GHK-Cu upregulating both the gene transcription of collagen genes and enhancing the enzymatic processing of procollagen into mature collagen fibers

Real-time polymerase chain reaction (PCR) was performed by using a kit (SYBR Premix EX Taq, Takara Bio Inc.) and the ABI PRISM 7300 real-time PCR system

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