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What we need to be thinking about is not only how we can create more GLP-1, but how we can restore our sensitivity to it so that we can feel full after eating. Natural Ways to Boost GLP-1 While research shows that GLP-1 medications are more effective than lifestyle tweaks to improve your GLP-1 (8), the following may modestly support weight management by promoting incretin sensitivity and bumping up your GLP-1 levels, according to physician Simran Malhotra, M.D

I started with Retatrutide alone in early January at 1 mg weekly

GLP-1 treatment starts at the lowest dose and increases gradually over a few weeks, so theres a built-in adjustment period before you reach a full dose

Some people also risk nutrient deficiencies (like B12) and pancreas issues