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Tirzepatide Constipation and Digestive Changes Tirzepatide constipation may feel similar but can vary in intensity from patient to patient

Liraglutide-induced Acute Gastroparesis, December 2018, Rai et al

Mean liver fat reduction was 82.4% by MRI-PDFF, with 86% of participants who had MASLD (metabolic-associated steatotic liver disease) at baseline achieving complete resolution (liver fat below 5%)

GLP-1 medications address some of these challenges directly, which is part of why demand for semaglutide and tirzepatide has been particularly strong among adults in their 50s and 60s