does naproxen deplete glutathione A Practical Approach to Avoiding Drug-Nutrient Depletions Non-steroidal anti-inflammatory drugs (NSAIDs) and

The most common issues were nausea (20% to 47% depending on dose), followed by constipation, diarrhea, and abdominal discomfort

And a recent study proves it once again

Diagnostic challenge: Differentiating neuropsychiatric manifestations from motor-induced cognitive slowness or medication side effects requires multidisciplinary assessment

Restoring B12 allows RBCs to form properly, oxygen delivery improves, and energy levels rise.The NHS notes B is needed for making healthy red blood cells and helps reduce tiredness and fatigue.) Nerve & myelin synthesis: B12 is also essential for maintaining the myelin sheath around nerves