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The authors would like to express their sincere gratitude to the staff of Kliniskt Forskningscentrum, Biobanken Norr, and Klinisk Kemi at Ume University Hospital for providing excellent research conditions, with special thanks to Camilla Ring, Inger Arnesj, Ingegerd Valinger, Kerstin Enquist Olsson, Gunilla Backman, and Lena Nordstrm