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When travelling by air: Carry the medicine in hand luggage , never in the hold, where temperatures can drop below freezing Carry a letter from your GP or clinical trial team confirming the need to carry injectable medication and associated sharps Be aware that airport security may require inspection of the medicine and associated equipment Check the airline's policy on carrying injectable medicines and cooling devices before travel Review NHS guidance on travelling with medicines and, where relevant, UK Civil Aviation Authority (CAA) guidance on carrying medicines and sharps For international travel, confirm refrigeration facilities at your destination in advance

These are resolution rates that no other medication has achieved

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This sequential approach (start tirzepatide now, reassess in 2028) is the most practical strategy for many patients