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A 2019 safety review examined 87 human studies on natural astaxanthin including 35 using doses of 12mg per day or higher and found no significant safety concerns or consistent adverse effects.11 Across those trials, approved or studied doses commonly ranged between 2mg and 24mg per day, and higher short-term doses (up to 40mg per day for several weeks) have also shown good tolerability in adults, with no serious events reported

Rashed MS, Ozand PT, Bennet MJ, Barnard JJ, Govindaraza DR, Rinaldo P

Accumulation of medium-chain acylcarnitines has been linked to defects in fatty acid oxidation and has also been observed in the metabolic disturbances characteristic of DKD [47, 48]

GLP-1 receptor agonist medicines are in high demand worldwide for treating diabetes and obesity