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So far, tirzepatide is probably no more likely to cause the rare and severe side effects outlined in this article

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That makes it different from medicines that act mainly through the GLP-1 pathway

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No randomised controlled trials have demonstrated efficacy in reducing disease activity or joint inflammation, and existing evidence consists only of preclinical studies and theoretical mechanisms

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Acute renal haemodynamic effects of glucagon-like peptide-1 receptor agonist exenatide in healthy overweight men

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