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Supplementary Table S3)

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The proinflammatory cytokines IFN- and TNF- are both elevated in the mucosa of IBD patients [93]

According to the National Institutes of Health, retinoic acid can support overall skin health and lessen the roughness of facial skin, reduce hyperpigmentation, and decrease the number and severity of fine facial wrinkles caused by photo-aging. It can also reduce inflammation and acne scarring