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Author contributions GT: Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing original draft, Writing review & editing

5-Amino-1MQ was developed as a pharmacological tool to inhibit NNMT activity, and preclinical studies have demonstrated that oral administration of 5-Amino-1MQ to obese rodents produces dose-dependent reductions in body weight and fat mass, improvements in glucose metabolism and insulin sensitivity, and increases in energy expenditure - remarkably, these effects occur without changes in food intake, indicating that 5-Amino-1MQ works through metabolic enhancement and increased caloric burn rather than appetite suppression

Remove the needle, apply light pressure with gauze, and dispose of the syringe in a sharps container