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More than 1,200 patients with T2DM complicated with obesity were randomly divided into 1mg SMG group, 2.4mg SMG group, or placebo group and given once a week in STEP2 research

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Third, the dose-response relationship is clear: higher target doses produce greater weight reduction, with 12mg weekly producing the peak 24.2% result

Research labs use it to study multi-hormonal metabolic signaling, energy homeostasis, and the interactions between overlapping incretin pathways