Glucomannan is the only ingredient with a permitted GB health claim for weight loss, conditional on a 3 g daily dose taken with adequate water as part of an energy-restricted diet
For example, in the SUSTAIN 5 clinical trial, patients with HbA1c levels of 8.0% or lower had their basal insulin doses reduced by 20% when starting semaglutide therapy to minimize the risk of low blood sugar
Given the above evidence, the multitarget properties of TCM formulations confer distinct benefits in modulating immune homeostasis, as summarized in Table 7
It enhances intracellular GSH synthesis and acts as both a direct and indirect antioxidant, scavenging major oxidants such as OH, NO 2 , and thiyl radicals, though less effectively against superoxide and hydrogen peroxide ( FIGURE 1 Given GSHs critical antioxidant role in the lungs, NAC has been extensively evaluated in respiratory diseases