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Deze andere geneesmiddelen kunnen zijn: via de mond in te nemen (orale) antidiabetesmiddelen (zoals metformine, thiazolidinedionen, sulfonylureumderivaten) of insuline

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Mechanistically, statins altered the bile-acid pool (notably lowering ursodeoxycholic acid, UDCA), which reduced signaling through the TGR5 receptor on intestinal cells, leading to less GLP-1 release

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These trials are essential milestones before retatrutide can come to market

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