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On the surface, it seems like a reasonable query

Oral intake undergoes breakdown from gastric acid and digestive enzymes, reducing compound stability before absorption occurs

Certain people should have extra screening, tighter monitoring, or alternative strategies: pregnancy or trying to conceive active cancer or recently treated cancer without oncology clearance uncontrolled autoimmune disease with high inflammatory burden severe allergic history or unpredictable reactions to injectables complex medication regimens that increase interaction concerns advanced liver or kidney disease that alters clearance and risk Cautious does not automatically mean no. It means individualized planning

see the Certificate of Analysis for the lot-specific result