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Additionally, the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and fibroblast growth factor 21 receptor (FG21R) also significantly influence these metabolic processes

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The observed beneficial effects of GLP-1 RAs likely translate into real-world settings, given that discontinuation rates may be lower for GLP-1 RAs than for other antidiabetic medications ( Additional investigations should focus on populations with optimal cardiovascular health in order to clarify the efficacy of GLP-1 RAs in primary prevention