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For example, you might drink water: When you take your morning medication Before or after meals Before going outside After a walk or workout When you get in the car Before bed, if it does not disrupt your sleep Add Flavor if Plain Water Is Hard to Tolerate Some patients find that plain water is less appealing while taking a GLP-1 medication

This leads to enhanced signaling that can significantly reduce hunger pangs and increase feelings of fullness

Acknowledgments The authors recognize the cooperation and enthusiasm of our participants

International guidelines highlight the need for more personalized treatment 1 , but the concept has not yet been systematically examined in randomized trials specifically designed to evaluate treatment responses in patients with different characteristics