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GLP-1 RAs not only ameliorate insulin resistance and microvascular injury [84], which are significant determinants of depression in T2DM, but also enhance dopamine metabolism and stimulate growth factor signaling pathways, suggesting potential neuroprotective functions [85,86]

Gradually increasing fiber intake while maintaining adequate hydration helps prevent gastrointestinal discomfort during the transition

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According to the most recent treatment guidelines, GLP-1 agonists may be most appropriate for people with type 2 diabetes who are at a high risk for heart disease or who already have heart disease