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The existing research on how GLP1RAs affect the absorption of oral medications is limited but indicates potential impacts on maximum concentration ( C max ), total drug exposure defined by AUC, and time to C max ( T max ) of coadministered oral drugs

the same study showed increased vessel density in vitro and in vivo and faster blood-flow recovery in a rat hind-limb ischemia model

Nevertheless, because of the limited age overlap between the study groups, residual age-related confounding cannot be completely excluded