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We hypothesized that serum lipids might play a role in sustaining histone acetylation independent of ACLY and ACSS2, because fatty acids oxidation produces acetyl-CoA and genes involved in oxidation are upregulated in DKO cells
Bertoldo A, Pizzol D, Yon DK, et al
Interestingly, metabolite analysis revealed decreased expression of acetyl-CoA, an essential precursor for lipogenesis, and downstream acetyl-CoA metabolites (Fig
GLUTATHIONE S -DERIVATIVES ACTIVATED BY GT AND PEPTIDASES Gamma-glutamyl transferase (EC2.3.2.2) catalyzes the transpeptidation and hydrolysis of the -glutamyl group of GSH and related compounds to an acceptor molecule, including water, amino acids, and peptides
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