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It is worth mentioning that this approval makes Trulicity the first type 2 diabetes drug approved for primary and secondary prevention populations to reduce the risk of MACE

Kapogiannis D, Boxer A, Schwartz JB, Abner EL, Biragyn A, Masharani U, et al

Copper delivery to copper-dependent enzymes including lysyl oxidase and superoxide dismutase is the mechanism most commonly proposed to link these observations