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Moreover, ROS exerts an important effect on microglia as the second messenger, modifying inflammatory gene transcription and, consequently, amplifying the inflammation

Likewise, hepatic mRNA levels of apoB100 and MTTP and serum VLDL-TG were higher in patients with steatosis ( n = 51) compared to patients with NASH ( n = 53), marking deterioration of VLDL assembly and export as important in the progression from steatosis to NASH [75]