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acknowledges support by the Czech Science Foundation (GA CR) grant 21-11563M and by the European Unions Horizon Europe program (ERC, TerpenCode, 101170268)

When I met with the editor of the BNF a year or two again she told me that any change in the treatment would have been based on evidence based research

Our aim is to achieve the most positive outcomes, regardless of whether a conservative or surgical approach to treatment is taken