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According to the National Institutes of Health, more than 30% of adults in the U.S

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62,100 Additionally, mitochondrial iron uptake, MPTP opening, and liver injury were significantly reduced in MCFU gene knockout mice exposed to APAP, 101 and selective chelation of iron in lysosomes with starch-desferal and the general iron chelator DFO also effectively prevented APAP-induced liver injury