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Safety Advisory: A dose-dependent increase in the risk of atrial fibrillation has been consistently observed in major trials, especially at the 4 g/day dose, prompting regulatory safety advisories ( Guideline Recommendations: Based on this evidence, major guidelines now endorse the selective use of icosapent ethyl

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With Health Conditions: Individuals with kidney problems should use caution, as high doses may increase the risk of kidney stones

Cancer Res 66(8):44104418 Soltani A, Salmaninejad A, JaliliNik M, Soleimani A, Javid H, Hashemy SI, et al (2018) 5Adenosine monophosphateactivated protein kinase: a potential target for disease prevention by curcumin