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It is the most abundant intracellular antioxidant in human cells and is often called the "master antioxidant" for its central role in redox homeostasis, enzymatic detoxification, and protection against oxidative damage

To enhance the pharmacological properties of the ruthenium catalyst, provide cancer selectivity for the treatment, and enable the treatment of challenging hypoxic tumors, the metal complexes were covalently conjugated to the side chains of polymers with a carbon fluorinated moiety that could co-deliver oxygen to the tumor

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Copper-GHK increases integrin expression and p63 positivity by keratinocytes