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Future large-scale, well-designed clinical trials will be essential to confirm their therapeutic potential, clarify the contribution of metabolic versus immunological effects, and define their role within the treatment algorithm of PsO and PsA

The development of rare adverse events, which may not occur until a patient has been on a drug for a number of years, is of concern, but until more patients are followed for an adequate period of time, the true safety of a drug cannot be stated or concluded

Neurosurgery (2006) 59(6):131323

It has not been approved by the Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease