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According to the prescribing information, patients typically begin at 0.25 mg once weekly, then increase to 0.5 mg after four weeks

: 0.2-0.3 (200-300 ) 1

International Meeting for Autism Research (Abstract) Chauhan A, Audhya T, Chauhan V (2011a) Increased DNA oxidation in the cerebellum, frontal and temporal cortex of brain in autism

The mechanism underlying these opposing gastrointestinal effects likely relates to semaglutides complex effects on gastrointestinal motility, with some patients experiencing accelerated intestinal transit while others experience overall slowing of gastrointestinal motility