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L-Carnitine's primary function is as a biological shuttle, but its metabolic impact extends across multiple pathways within the mitochondrial energy production system

The highest monotherapy dose studied is 4.5 mg per week (Lancet 2021 Phase 2)

A mediation analysis revealed that while a change in body weight was the primary contributing factor (72%) to the reduction in SBP, other factors, including estimated glomerular filtration rate and HbA 1c , were also involved to a lesser degree

Patients seeking physician-guided medical weight loss may discuss all available treatment options during consultation to determine the most appropriate path forward