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Research Evidence and Trial Sources The strongest evidence base comes from ClinicalTrials.gov trial records, peer-reviewed review articles in journals such as Metabolism , Peptides , and Nature Reviews Drug Discovery , plus sponsor-published Phase 3 readouts that still require peer-reviewed confirmation

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Primary end point 3 : Change in BMI (%) from baseline to week 68 Relevant supportive secondary end points 4 : Change in body weight (%) from baseline to week 68 Proportion of patients achieving 5% BMI reduction from baseline to week 68 Additional parameters from Prescribing Information 4 : Proportion of patients achieving 10% and 15% BMI reductions from baseline to week 68 BMI, body mass index