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If you are considering GLP-1 therapy or are already using it and planning pregnancy, a genetic assessment can support a conversation with your provider about whether early intervention before conception is optimal for your situation, or whether alternative management strategies may better align with your family planning timeline

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The CXCR4 receptor appears to be critically involved in many of these effects, particularly in regulating autophagy, IGF-1 abundance, Akt phosphorylation, and oxidative stress, as AMD3100 reversed these protective actions