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These updated warnings include further advice for patients using oral contraceptives: Patients taking tirzepatide are advised to switch to a non-oral contraceptive or add a barrier method of contraception for 4 weeks after first taking the medicine and for 4 weeks after each increase in the dose

The results revealed that, except for the metabolic organs liver and kidney, the tumor tissue exhibited the highest fluorescence intensity, further confirming the excellent tumor targeting of NP4 (Fig