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At 6 hpi, mice were intraperitoneally treated with 10 mg kg 1 Rif, alone or with 100 mg kg 1 KL1 in 7% DMSO, 40% PEG300 and 53% sterile H 2 O

Cancer Res (2005) 65:5696702

By contrast, the effects of anti-cancer agents that seek to induce ferroptosis via GSH depletion (e.g., cyst(e)inase, [Cramer et al, 2017]) could be blunted if combined with chemotherapeutics such as gemcitabine and HU, which inhibit the consumption of GSH by nucleotide metabolic processes and also slow DNA replication by blocking elongation (Heinemann et al, 1990

Neurosteroids that can permeate cell membranes can be localized within different intracellular compartments