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They are integrated into the membranes by 12 transmembrane regions and contain a STAS domain, found in SULTRs and with a significant similarity to bacterial a nti- s igma factor antagonists (Takahashi et al., 2011a,b)

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Here are the most notable findings from a study involving mice with growth hormone deficiencya condition that leads to stunted growth, reduced lean mass, and increased abdominal fat [17]: Enhanced growth and lean body mass: Growth hormone deficient (GHD) mice exhibited approximately 20% less lean body mass than normal, struggling to attain regular body size or weight