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Funding This work was supported by the European Respiratory Society (ERS Gold Medal in ARDS to GVdB), the Research Foundation Flanders (FWO) Grant G091918N to GVdB, the European Research Council Advanced Grant (AdvG-2017-785806 to GVdB) from European Unions Horizon 2020 research and innovation program and the Methusalem program of the Flemish Government (METH/14/06 to GVdB and LL via the KU Leuven)

HCG ($350/month) can be added alongside TRT to maintain testicular function and sperm production

A bubble that resolves within 24 hours without associated symptoms is typically benign

Carnosine acts to reduce the rate of formation of a variety of substances that can be factors in the development or exacerbation of diseases including diabetes, atherosclerosis, chronic renal failure, and Alzheimers disease