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Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology

Ratio Consistency: Guarantees that every aliquot drawn from the vial contains the exact same 50/10/10/10 ratio

To determine whether this transient ratio change reflected genuine redox shifts or imaging artifacts, we introduced mutations to roGFP2, replacing its cysteine residues with serines, thus rendering it inactive