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In fact, extensive cardiovascular outcome trials have demonstrated that several GLP-1 agonists provide cardiovascular benefits rather than harm

All authors gave their final approval and agree to be accountable for all aspects of the work

Back Karamanou, M, Protogerous, A, Tsoucalas, G, et al (10 Jan 2016) 'Milestones in the history of diabetes mellitus: The main contributors', World Journal Diabetes , 7/1, 1-7

The duration of fatigue can vary widely from person to person, depending on individual factors such as metabolism, dosage, and how the body adapts to the medication