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A systematic review and meta-analysis by Bray and colleagues assessed the effects of GLP-1RAs on biomarkers of inflammation and oxidative stress in individuals with T2DM, and reported a significant reduction in CRP, TNF-, malondialdehyde, along with significant increases in adiponectin levels [96]

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It does not damage local tissues and has no known systemic side effects

The Skeletal Effects of a Growth Hormone- Derived Peptide (AOD9604) in the Aged Rat Model of Postmenopausal Osteoporosis