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Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2
When combined with insulin or sulfonylureas, GLP-1 agonists may increase the risk of hypoglycemia, requiring dose adjustments of these medications
Approved for use in the United States since 2017, it has recently seen a surge in popularity attributed to reports of off-label use for weight- loss promotion
When to Startand When Not To According to the package insert, GLP-1 therapy for obesity is indicated for individuals with a BMI 27 with a weight-related condition, or a BMI 30 alone
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