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Treatment discontinuation due to gastrointestinal events occurred in a minority of patients, and overall, serious adverse events were similar to those with the placebo

A randomized, double-blind, placebo-controlled, parallel-group study showed that among the patients with T2DM treated with EX monotherapy, EX could improve glycated hemoglobin, fasting blood glucose, and postprandial blood glucose control, reduce weight, improve cell function, and adjust blood pressure

Cost, patient preference, and side effects still matter, but they are all secondary to what the insurance will actually pay for. Zepbound is for adults with obesity or overweight who also have weight-related health conditions such as type 2 diabetes, cardiovascular disease, or high blood pressure

There is no completed head-to-head trial proving one is superior in the same population