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In the case of miRNA therapies in RA, local delivery (intraarticular) might be beneficial, because a greater amount of active substance might reach the site of RA progression and possible systemic effects of miRNAs could be reduced

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This paper describes a new gene-expression profile, including YM1 and FIZZ1, in nematode-elicited (alternatively activated) macrophages with the functional capacity to suppress target-cell proliferation