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This may have to do with its interaction with other hormones, such as serotonin (known popularly as the happy hormone), which is a neurotransmitter involved in mood and appetite regulation, and sex hormone-binding globulin (SHBG)

It is possible the final answer is a process impurity, possible it is a deliberate adulterant like the sibutramine INTERPOL found elsewhere, and possible it is something nobody has guessed