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This resin has high binding affinity and specificity to the Glutathione S-transferase (GST) protein

Indoxyl sulfate induces endothelial dysfunction, through the increased production of NADPH oxidase-derived reactive oxygen species (ROS), the increased expression of intercellular adhesion molecule-1 (ICAM-1) and E-selectin, factors playing key roles in monocyteendothelial interactions (70, 71)

AHK-Cu may potentially become a member of the expanding family of copper-based therapies targeted at neuronal preservation, inflammation reduction, and regeneration if research keeps moving forward in the same direction, combining computational discoveries with useful biomedical testing