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In the SELECT trial, over an average of 40 weeks of follow-up, a 20% reduction in the occurrence of the three-point composite cardiovascular endpoint (cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke) was found in overweight and obese, non-diabetic adults with once-weekly subcutaneous semaglutide (2.4 mg) [83]
Studies regarding cytotoxicity are rare compared to the numerous reports describing antimicrobial activities
As a deficiency in magnesium can cause unwanted side effects during a detox, I recommend taking a magnesium citrate supplement, such as the one by Rootcology or Pure Encapsulations , at bedtime