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Sakaguchi for her technical support and insightful discussion

Epinephrine exerts -adrenergic vasoconstrictive effects , increasing aortic diastolic pressure and coronary perfusion during cardiopulmonary resuscitation, and -adrenergic effects , increasing heart rate and myocardial contractility to facilitate return of spontaneous circulation (ROSC)

Endurance athletes may also deplete B12 stores faster due to increased metabolic demands and potential gastrointestinal stress from long training sessions

Future research is needed to better understand the relationship between age and the effects of paraxanthine and caffeine on cognitive function