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[5] The severity of SCD is generally less when compared to PCD as the plasma carnitine levels are relatively higher and hence easier to manage.[3][8]Patients with SCD, in general, do not have hepatic or cardiac involvement

The mechanism of these changes will however require further research

The potential of the emerging Glucagon-like Peptide-1 (GLP-1) Agonists in changing the current clinical practice guidelines is crucial to analyze, especially when it comes to real-world scenarios

The biological mechanism rests on column 1 (GHRH-R) raising pulse amplitude while column 2 (GHS-R1a) raises basal release frequency and antagonizes somatostatin tone