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However, the lack of significant results favoring a neuroprotective effect of GLP-1R agonists may be due to early business-related withdrawal of sponsor support (Mullins et al., 2019)

The severity varies considerably among individuals, with some experiencing minimal discomfort while others find these effects significantly impact quality of life

found that exogenous -KG mimics glutaminase-mediated ferroptosis, while using a transaminase inhibitor, amino-oxyacetate (AOA), reverses ferroptosis [85, 86]