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Gipr AP-KO mice on chow diet had comparable body weight, fat mass and lean mass to control Gipr AP-GFP animals (Fig

8,9 The pentadecapeptide body protective compound (BPC)-157 ( Mr 1419), with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, a 15-amino acid fragment of the BPC peptide in gastric juice, is thought to be essential for BPCs activity and has been fully characterized and investigated

AOD-9604 vs GLP-1 S GLP-1 S (semaglutide) works through an entirely different system than AOD-9604: it activates GLP-1 receptors to slow gastric emptying, increase satiety, and improve glycemic control, producing weight loss primarily by reducing food intake rather than by acting on fat cells directly

Harb et al