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So this is my personal opinion, but you will always have segments of the population that are resistant to using pharmaceuticals or want to try natural solutions first, so products like berberine arent going to go away. As for gut health, which has attracted more awareness as GLP-1 drugs have gained traction, SPINS data show sales of probiotic supplements were down 7.6% in the year to October 6

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In some cases, yes

What you need to evaluate carefully is the regulatory environment: compounded GLP-1 availability is under ongoing FDA review in 2026