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The TRIUMPH-4 trial revealed a notable incidence of dysesthesia, an abnormal sensation affecting touch perception that can cause numbness, tingling, or unusual skin sensitivity

I generally tell people that if theyre having mild nausea or constipation, see if youre able to ride it out, he says

Their study also showed that nearly 40% of GLP-1 users experience gastrointestinal side effects nausea, vomiting, diarrhea, constipation, and altered appetite and satiety regulation

Other times Ill see someone Ive followed for yearsan acquaintance, a celebrity, or a content creatorposting photos where theyre suddenly several sizes smaller, a weight loss so dramatic it likely wouldnt have been possible without pharmaceutical assistance