These drugs are associated with a decreased risk of stroke, heart attacks, and the development of heart failure. A study involving patients with preexisting cardiovascular disease and overweight or obesity without diabetes found that a weekly semaglutide dose of 2.4 milligrams (mg) reduced the risk of death from cardiac events, nonfatal myocardial infarction, or nonfatal stroke
GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders
Contact your GP if you experience: Persistent fatigue, weakness, or shortness of breath (possible anaemia) Numbness, tingling, or balance problems (possible B12 deficiency) Muscle cramps, spasms, or irregular heartbeat (possible magnesium or potassium deficiency) Bone pain or frequent fractures (possible vitamin D or calcium deficiency) Poor wound healing or frequent infections (possible zinc or vitamin C deficiency) Seek urgent medical attention (call 111 or 999 as appropriate) for severe palpitations, chest pain, fainting, or signs of severe allergic reaction
Drink enough water throughout the day so your urine is light yellow